Process R&D

Processes for products which are to be produced on a larger scale undergo a systematic program to study the relevant parameters influencing the yield and quality of the target product. Initial testing for safety parameters will be undertaken at this stage.

Our R&D experts can rapidly develop scalable, robust and cost-effective chemical processes and optimize reaction conditions for your complex, intermediates or APIs

Our expertise and services include:

  • Evaluation, scouting and development of new synthesis routes for your target molecule.
  • Optimization of reaction conditions to reduce manufacturing costs by classical methods or statistical design of experiments (DOE).
  • Rapid screening of reaction conditions (e.g. Hydrogenation, Carbonylation, CX-coupling etc.) using a Symyx platform.
  • Development of reliable analytical methods for in-process control for intermediates and APIs.
  • Scale-up of new and existing routes in glass reactors and fixed reactors capacities ranging from
    50 L to 2KL to fulfill your requirements and meet your timelines.
  • Development of robust and scalable crystallization procedures for intermediates and APIs.
  • Synthesis of APIs for preclinical and clinical studies up to phase II.

Our solutions are based on deep industrial experience and innovative processes, which generate valuable new IP rights for you and also help you to meet your Cost of Goods target.